{"id":22373,"date":"2026-05-20T08:40:25","date_gmt":"2026-05-20T08:40:25","guid":{"rendered":"https:\/\/dmu.ae\/home\/?post_type=blog_post&p=22373"},"modified":"2026-05-21T08:42:56","modified_gmt":"2026-05-21T08:42:56","slug":"college-of-pharmacy-faculty-and-students-publish-research-on-plant-based-therapies-for-uterine-fibroids-in-international-peer-reviewed-journal","status":"publish","type":"blog_post","link":"https:\/\/dmu.ae\/home\/blog-post\/college-of-pharmacy-faculty-and-students-publish-research-on-plant-based-therapies-for-uterine-fibroids-in-international-peer-reviewed-journal\/","title":{"rendered":"College of Pharmacy Faculty and Students Publish Research on Plant-Based Therapies for Uterine Fibroids in International Peer-Reviewed Journal"},"content":{"rendered":"\n

The College of Pharmacy at Dubai Medical University (DMU) announces the publication of a research article by Professor Naglaa Gamil Shehab<\/strong>, Professor in the Pharmaceutical Sciences Department \u2013 Dubai Medical University, in collaboration with undergraduate pharmacy students. The study was published in Pharmaceuticals<\/em> (MDPI), a reputable international peer-reviewed journal, on March 23, 2026<\/strong>.<\/p>\n\n\n\n

Titled \u201cPhytotherapeutic Intervention in Monosodium Glutamate-Induced Uterine Dysfunction: Efficacy of Lepidium sativum, Prunus armeniaca, Stachys palustris, and Solenostemma argel,\u201d<\/em> the research investigates the therapeutic potential of four medicinal plant extracts in addressing uterine fibroids \u2014 a condition that affects an estimated 70\u201380% of women worldwide by the age of 50 and is a leading cause of hysterectomy.<\/p>\n\n\n\n

Uterine fibroids are benign tumors that significantly impact women\u2019s reproductive health, quality of life, and fertility. Current treatment options \u2014 including hormonal therapies and surgical interventions \u2014 are often limited by high costs, side effects, and concerns about fertility preservation. This study sought to explore plant-based, cost-effective, and minimally invasive alternatives.<\/p>\n\n\n\n

Using a preclinical rat model, the research team evaluated four medicinal plant extracts \u2014 Lepidium sativum<\/em> (garden cress), Prunus armeniaca<\/em> (apricot), Stachys palustris<\/em> (marsh woundwort), and Solenostemma argel<\/em> (argel) \u2014 for their antioxidant activity, hormonal modulation, and protective effects on uterine tissue. The plants were selected based on their ethnopharmacological significance in Middle Eastern, North African, and European traditional medicine, as well as emerging scientific evidence supporting their roles in reproductive health.<\/p>\n\n\n\n

Key findings of the study showed that Lepidium sativum<\/em><\/strong> and Stachys palustris<\/em><\/strong> demonstrated the most significant therapeutic effects, restoring antioxidant enzyme levels (catalase, glutathione, and superoxide dismutase), reducing estrogen receptor expression, and reversing fibroid-like structural changes in uterine tissue. Solenostemma argel<\/em> and Prunus armeniaca<\/em> also showed promising effects through distinct antioxidant and hormonal mechanisms.<\/p>\n\n\n\n

The study was co-authored by pharmacy students Fatimah Muaamar Noori, Nikoo Ali Jalali, Rodiana Mohamed Fouad Saber, and Zainab Safieldin Abdalla Mohamed<\/strong> \u2014 reflecting the College of Pharmacy\u2019s dedication to nurturing the next generation of pharmaceutical scientists through hands-on research experience.<\/p>\n\n\n\n

The study provides important preclinical evidence supporting the use of select plant extracts in managing fibroid-associated oxidative stress and hormonal imbalance. The authors call for further clinical research to validate these findings and translate them into effective, evidence-based therapies for women\u2019s health.<\/p>\n\n\n\n

Full article (open access): <\/strong>https:\/\/www.mdpi.com\/1424-8247\/19\/3\/521<\/a> DOI: 10.3390\/ph19030521<\/p>\n","protected":false},"excerpt":{"rendered":"

The College of Pharmacy at Dubai Medical University (DMU) announces the publication of a research article by Professor Naglaa Gamil Shehab, Professor in the Pharmaceutical Sciences Department \u2013 Dubai Medical University, in collaboration with undergraduate pharmacy students. The study was published in Pharmaceuticals (MDPI), a reputable international peer-reviewed journal, on March 23, 2026. Titled \u201cPhytotherapeutic <\/p>\n","protected":false},"author":1,"featured_media":22374,"comment_status":"closed","ping_status":"closed","template":"","tags":[],"blog-category":[55],"class_list":["post-22373","blog_post","type-blog_post","status-publish","has-post-thumbnail","hentry","blog-category-pharmacy"],"acf":[],"yoast_head":"\nCollege of Pharmacy Faculty and Students Publish Research on Plant-Based Therapies for Uterine Fibroids in International Peer-Reviewed Journal - Dubai Medical University<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/dmu.ae\/home\/blog-post\/college-of-pharmacy-faculty-and-students-publish-research-on-plant-based-therapies-for-uterine-fibroids-in-international-peer-reviewed-journal\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"College of Pharmacy Faculty and Students Publish Research on Plant-Based Therapies for Uterine Fibroids in International Peer-Reviewed Journal - Dubai Medical University\" \/>\n<meta property=\"og:description\" content=\"The College of Pharmacy at Dubai Medical University (DMU) announces the publication of a research article by Professor Naglaa Gamil Shehab, Professor in the Pharmaceutical Sciences Department \u2013 Dubai Medical University, in collaboration with undergraduate pharmacy students. 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